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‘‘Synthesis of Phosphonate Analogues of the Antibiotic Moenomycin A12’’

 

Khalid Abu Ajaj, University of Leipzig, Leipzig, July 2002

 

supervised by Prof. Dr. Peter Welzel

 

In the context of this work, C-glycosid-di- und trisaccharide-building blocks of the antibiotic moenomycin A12 were synthesised on the basis of b-d-Galactose-pentaacetate. The starting material was transferred in galactoheptonamide. The unit F of the disaccharide component has all substituents, which the unit F of the Moenomycins A12 has. The prepared synthesis way should be suitable for the synthesis of other analogues.

 

to the thesis (PDF-file): Summary, All,

or through Leipzig University Publication Server

 

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